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Genetically and genomically, the human and the mouse are very similar, with many of Early genetic maps of the mouse genome, based on recombinational.
Table of contents

On line registration. Practical information Institut Pasteur. In English.

Mouse Genetics Group Database

Credits for a Master 2 degree Paris Sud. Doctoral School Module. Institut Pasteur Diploma. University diploma Paris Diderot. The themes of the course: The theoretical part of this course deals, in particular, with genetic analysis of mendelian and quantitative traits, phenotypic analysis of genetic variants, early embryo biology, pluripotent stem cells, cellular and molecular mechanisms controlling embryogenesis, models to study oncogenes and tumor suppressor genes, methods to study cell lineage in mouse embryos, genome editing and conditional expression systems for transgenes, optogenetic approaches and the role of small RNAs.

Program of the Mouse genetics course - Academic year. More informations Director s. Cohen-Tannoudji Institut Pasteur , A. Lucas-Hourani Institut Pasteur , S. Bouthillier, C. Bangrazi, J. Mevel, S. Rebessi, G. Doria, and G. Biozzi Inheritance of immune responsiveness, life span, and disease incidence in interline crosses of mice selected for high or low multispecific antibody production.

Journal of Immunology — Curtsinger, J. Fukui, D. Townsend, and J.

Vaupel Demography of genotypes: Failure of the limited life-span paradigm in Drosophila melanogaster. Science — Van Zant. Eigenmann, J. Amador, and D. Patterson Insulin-like growth factor I levels in proportionate dogs, chondrodystrophic dogs and in giant dogs. Acta Endocrinologica — Patterson, and E. Froesch Body size parallels insulin-like growth factor I levels but not growth hormone secretory capacity. Falconer, D. Gauld, and R. Roberts Cell numbers and cell sizes in organs of mice selected for large and small body size. Genetical Research — Finch, C. Chicago: University of Chicago Press.

Pike, and M. Witten Slow mortality rate accelerations during aging in some animals approximate that of humans. Gelman, R. Watson, R. Bronson, and E. Yunis Murine chromosomal regions correlated with longevity. Hillesheim, E. Stearns Correlated responses in life-history traits to artificial selection for body weight in Drosophila melanogaster.

Evolution — Jackson, A. Fornes, A. Galecki, R. Miller, and D. Kenyon, C. Chang, E. Gensch, A.

Genetics of Wild Mice Behavior - Hopi Hoekstra

Rudner, and R. Tabtiang A C. Nature — Kimura, K. Tissenbaum, Y. Liu, and G.

Ruvkun daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Lerner, A. Yamada, and R. European Journal of Immunology — Li, Y. Deeb, W. Pendergrass, and N. Wolf Cellular proliferative capacity and life span in small and large dogs. Lipman, R. Dallel, and R. Bronson Lesion biomarkers of aging in B6C3F1 hybrid mice.


  • Negotiate and Settle Your Debts!
  • Sleeping Beauty, A Legend in Progress.
  • Inbred strains;
  • Genetics of the Mouse.

Masoro, E. McCarter, R. Shimokawa, Y. Ikeno, Y. Higami, G. Hubbard, B. Yu, and C. McMahan Physical activity as a factor in the action of dietary restriction on aging: Effects in Fischer rats. Aging: Clinical and Experimental Research — Migliaccio, E. Giorgio, S. Mele, G. Pelicci, P. Reboldi, P. Pandolfi, L. Lanfrancone, and P. Pelicci The p66shc adaptor protein controls oxidative stress response and life span in mammals.

Miller, R. Future landmarks in biomedical gerontology. Journal of the American Geriatrics Society — Mechanisms of Ageing and Development — Austad, D. Burke, C. Chrisp, R. Dysko, A. Galecki, and V. Monnier Exotic mice as models for aging research: Polemic and prospectus. Neurobiology of Aging — Bookstein, J.

Why mouse genetics?

Engle, J. Kim, L. Mullins, and J. Faulkner Candidate biomarkers of aging: Age-sensitive indices of immune and muscle function co-vary in genetically heterogeneous mice. Chrisp, and A. Galecki CD4 memory T-cell levels predict lifespan in genetically heterogeneous mice. Chrisp, and W. Atchley a Differential longevity in mouse stocks selected for early life growth trajectory. Dysko, C. Seguin, L. Linsalata, G. Buehner, J. Harper, and S. Austad b Mouse Mus musculus stocks derived from tropical islands: New models for genetic analysis of life history traits.

Miskin, R. Masos Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity. Olshansky, S. Carnes, and C. Cassel In search of Methuselah: Estimating the upper limits to human longevity. Orentreich, N. Matias, A. DeFelice, and J. Zimmerman Low methionine ingestion by rats extends life span. Journal of Nutrition — Roberts, R. Heredity — Samaras, T.

Mouse genetics | Institut Pasteur

Storms Impact of height and weight on life span. Bulletin of the World Health Organization — Smith, J. Proceedings of the Royal Society of London. Series B-Biological Sciences — Sprott, R.

Introduction to Mouse Genetics

Tuffery, A. Journal of Pathology and Bacteriology — Weindruch, R. Witkowski, J. Miller Increased function of P-glycoprotein in T lymphocytes of aging mice. Yu, B. Masoro, and C. McMahan Nutritional influences on aging of Fischer rats: I. Physical, metabolic, and longevity characteristics. Journal of Gerontology — What can social science, and demography in particular, reasonably expect to learn from biological information?

There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. The book also takes a look at the various ethical and legal concerns that such data collection entails. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website.

Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book. Switch between the Original Pages , where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text. To search the entire text of this book, type in your search term here and press Enter. Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available. Do you enjoy reading reports from the Academies online for free?

Sign up for email notifications and we'll let you know about new publications in your areas of interest when they're released. Office phone Email s transgenics mskcc. Services Production of transgenic mice: transgene DNA purification; transgene DNA injection; genotyping of founder mice; and transgene transmission to progeny. Management of breeding colonies at Long Island City.